{"id":6323,"date":"2018-02-20T10:43:35","date_gmt":"2018-02-20T15:43:35","guid":{"rendered":"http:\/\/www.monsffa.ca\/?p=6323"},"modified":"2018-02-20T10:43:35","modified_gmt":"2018-02-20T15:43:35","slug":"doctors-use-thrones-murder-to-explore-treatments","status":"publish","type":"post","link":"https:\/\/www.monsffa.ca\/?p=6323","title":{"rendered":"Doctors use Thrones\u2019 murder to explore treatments"},"content":{"rendered":"<div class=\"copy-snippet fontset1 scale3\">\n<article class=\"art\">\n<header>\n<hgroup>\n<h1 data-bind=\"text: articleTitle\">DEADLY RESULTS: Doctors use Thrones\u2019 murder to explore treatments<\/h1>\n<\/hgroup>\n<ul class=\"art-byline\">\n<li class=\"art-source\" data-bind=\"text: issueTitle\">Montreal Gazette\u00a0 <time data-bind=\"text: shortDateString\">20 Feb 2018\u00a0 <\/time>SHERYL UBELACKER<\/li>\n<\/ul>\n<\/header>\n<div data-bind=\"foreach: articleBlocks\">\n<p data-bind=\"text: $data\">TORONTO Game of Thrones fans may have shed few tears over the poisoning death of King Joffrey I Baratheon, a nasty character if ever there were one. But could real-world medicine have saved the young monarch?<\/p>\n<p data-bind=\"text: $data\"><a href=\"http:\/\/www.monsffa.ca\/wp-content\/uploads\/2017\/04\/dragon-at-crime-scene.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-4830 alignleft\" src=\"http:\/\/www.monsffa.ca\/wp-content\/uploads\/2017\/04\/dragon-at-crime-scene-300x295.jpg\" alt=\"\" width=\"177\" height=\"174\" srcset=\"https:\/\/www.monsffa.ca\/wp-content\/uploads\/2017\/04\/dragon-at-crime-scene-300x295.jpg 300w, https:\/\/www.monsffa.ca\/wp-content\/uploads\/2017\/04\/dragon-at-crime-scene.jpg 390w\" sizes=\"auto, (max-width: 177px) 100vw, 177px\" \/><\/a>It was an intriguing question for Will Wu, a third-year medical student at the University of Toronto, who teamed up with two physicians at St. Michael\u2019s Hospital to explore what steps could have been taken to try to resuscitate Joffrey, one of several characters to experience grisly deaths in of the wildly popular HBO series.<\/p>\n<p data-bind=\"text: $data\">\u201cThese characters don\u2019t get saved in the story, but there are ways to save them in real life,\u201d said Wu of Ottawa, who describes himself as a \u201ccasual\u201d aficionado of Game of Thrones.<\/p>\n<p data-bind=\"text: $data\">Joffrey, the arrogant and cruel king who sat on the Iron Throne ruling the Seven Kingdoms, unwittingly drinks poisoned wine at his wedding feast in season 4. He chokes, collapses and dies as blood pours from his eyes and nose.<\/p>\n<p data-bind=\"text: $data\">\u201cWe think the toxin caused him to go into a seizure and then into cardiac arrest, where the heart stops,\u201d said Wu, whose \u201ccase report\u201d on treating the character was co-written with emergency medicine specialists Dr. Emily Austin and Dr. Steve Lin, and published on the CanadiEM website.<\/p>\n<p data-bind=\"text: $data\">The poison that felled Joffrey (portrayed by Jack Gleeson) was called \u201cthe strangler\u201d and it created a range of symptoms that weren\u2019t consistent with toxins familiar to modern-day doctors, said Austin, who has a specialty in pharmacology and toxicology.<\/p>\n<p data-bind=\"text: $data\">\u201cBut in general, any type of cardiac arrest associated with a poison, you can apply certain treatments and really nothing was done for this poor guy, although he\u2019s a horrible character,\u201d she said. \u201cHad something been done, he may have stood a chance to be resuscitated.\u201d<\/p>\n<p data-bind=\"text: $data\">Treatment would have involved a number of steps \u2014 checking the pulse, performing CPR and maintaining an airway.<\/p>\n<p data-bind=\"text: $data\">A defibrillator to shock the heart back to life wouldn\u2019t have gone amiss, either, Austin conceded.<\/p>\n<p data-bind=\"text: $data\">\u201cAnd then it moves on to the specific toxicology stuff where you start thinking, \u2018Is there a specific antidote that I could give to this person, given the constellation of symptoms that they have?\u2019 \u201d<\/p>\n<p data-bind=\"text: $data\">In some cases of poisoning induced cardiac arrest, doctors have been successful in resuscitating a patient with an IV injection of a solution of lipids. One theory suggests that these fats absorb and compartmentalize certain toxins, keeping them out of tissues where they would have deadly effects.<\/p>\n<p data-bind=\"text: $data\">The King Joffrey case report is the second based on a Game of Thrones character that was written by the team and published on CanadiEM, a website aimed at emergency medicine practitioners. The previous article discussed the role of hypothermia in the case of Jon Snow (played by Kit Harington), who was stabbed multiple times and left to bleed out in freezing temperatures.<\/p>\n<p data-bind=\"text: $data\">Austin called the Joffrey article suggested by Wu \u201ca great project for a medical student, because it allows you to do a bit more reading around toxin-induced cardiac arrest.\u201d<\/p>\n<p data-bind=\"text: $data\">\u201cBut taking a step back, I think one of the goals to the article is just to sort of highlight that toxin-induced cardiac arrest can be managed a little bit differently and &#8230; there are some special treatments,\u201d compared with those used for cardiac arrests caused by other factors, she said.<\/p>\n<p data-bind=\"text: $data\">\u201cIt\u2019s just a good reminder of some of those differences and some of the options we have to treat these patients.\u201d<\/p>\n<\/div>\n<p><span id=\"m5ecda13ed8\">cialis properien <a href=\"http:\/\/amerikabulteni.com\/2017\/06\/10\/hangi-eyalet-en-cok-hangi-kelimeyi-dogru-yazmakta-zorlaniyor\/\">amerikabulteni.com<\/a> This sexual dysfunction changed man&#8217;s life by stealing away his pleasurable moments. 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But could real-world medicine have saved the young monarch? It was an &hellip; <a href=\"https:\/\/www.monsffa.ca\/?p=6323\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Doctors use Thrones\u2019 murder to explore treatments<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[811],"tags":[416,1066],"class_list":["post-6323","post","type-post","status-publish","format-standard","hentry","category-science-and-technology","tag-game-of-thrones","tag-medicine"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.monsffa.ca\/index.php?rest_route=\/wp\/v2\/posts\/6323","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.monsffa.ca\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.monsffa.ca\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.monsffa.ca\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.monsffa.ca\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6323"}],"version-history":[{"count":1,"href":"https:\/\/www.monsffa.ca\/index.php?rest_route=\/wp\/v2\/posts\/6323\/revisions"}],"predecessor-version":[{"id":6324,"href":"https:\/\/www.monsffa.ca\/index.php?rest_route=\/wp\/v2\/posts\/6323\/revisions\/6324"}],"wp:attachment":[{"href":"https:\/\/www.monsffa.ca\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6323"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.monsffa.ca\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6323"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.monsffa.ca\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6323"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}